The refuge, a former hospice for travellers from the Santuario della Madonna delle Nevi, is situated on the shores of Lake Miserin, in an excellent position in the Parco del monte Avic.
It can be reached in a one hour walk from Parco Nazionale del Gran Paradiso (Gran Paradiso National Park).

Pont-Saint-Martin motorway exit. Having reached the stop sign straight after the Pont-Saint-Martin exit on the A5, turn left and follow the signs for Aosta. Go past the towns of Donnas and Bard until you reach a roundabout, at this point turn left towards the valley of Champorcher.
Go past the towns of Hône and Pontboset and carry on through the valley for approximately 13 kilometres until you reach the centre of Champorcher in the hamlet of Castello. Take the first road which branches off to the right and follow the signs for the Dondena refuge. Carry on for several kilometres until you reach the unsurfaced road. From the start of the unsurfaced road, carry on for a further 6 kilometres until you reach a "divieto" (No Entry) sign and a parking area. The road starts here which first of all takes you to the Dondena refuge (15 minutes) and carrying on reaches the Miserin refuge (1 hour 30 minutes walk).

The nearest train station is in Pont-Saint-Martin.
An hourly local train connects with the town of Hône (14 trips a day), and from here a Scheduled Coach service (approximately 6 trips a day) will take you to the town centre of Champorcher.